Diana

With All My Heart! I: Now creates 3 Heart Breakers. This is the go-to Epiphany for many builds as it has the highest generation of Heart Breakers you can easily achieve.

With All My Heart! II: The card now only makes 1 Heart Breaker but can draw 2 [Exhaust / Bullet] cards. This is not an especially strong Epiphany in very optimized setups, for most scenarios; however, it can help to alleviate issues with card-order in some decks or recover from not exhausting all of your [Bullet] cards on previous turns. For example, it can help if you are forced to discard some Heart Breakers early in a round but don’t want them to clog your draw next turn, so you can redraw them later in the same turn via this card.

With All My Heart! III: Now becomes a card that changes all 1-cost or lower [Exhaust] cards in hand into Heart Breakers. This can be quite strong with certain characters who can make a lot of 1-cost [Exhaust] cards, like Kayron, or in specific boss scenarios where they make a lot of [Exhaust] status ailments of 1-cost. However, it requires you to know what specific scenario you are building towards and is not a general-use recommendation.

With All My Heart! IV: Changes to a 2-cost that still creates 2 Heart Breakers but also applies [Quietus] to all [Bullet] cards in hand. This is extremely strong as it can functionally double the value of many [Bullet] cards and can be played for free, as it has [Quietus] itself; however, it can be hard to achieve the perfect timing on this to get its full value. It also commonly wants to be played with With All My Heart! I, which can make it awkward to farm as dual Epiphany decks require careful planning in Chaos to achieve. Playing Diana decks effectively with this Epiphany present can also mostly eliminate deck-clogging issues, thanks to most Heart Bullets discarded being played, which also exhausts them.

With All My Heart! V: Becomes an upgrade that creates 2 Heart Breakers in hand at the start of the turn and an additional 1 (for a total of 3) if less than 5 are currently owned. This can be a great way to passively generate Heart Bullets on Diana; however, it requires a lot of handspace at the start of the turn, which can be hard to play around–especially since this is an option that would likely get more value in more Sub-DPS/Supportive Diana decks that might not have as much free handspace to allocate to her.

Neutral: Target Neutral Epiphany: Draw 1.
Draw 1 gives an efficiency similar to Divine's, enabling a much easier cycle and saving save data points for other areas of set-up like Neutral cards.

Divine: Which Divine Epiphany to go for will depend on what your team needs and which Epiphany you chose, but here are the main ones to look out for if you have spare Save Data: Draw 1.

C'mere、Milk & Pong! I: The card now generates Heart Breakers instead of Heart Shakers and applies 1 Resonance for the next 3 extra attacks of a different combatant. This is a great option for building Resonance in more supportive or sub-dps Diana builds, typically builds played with DPS like Renoa or Hugo, who also do a lot of extra attacks. However, it can be hard to get value from its additional effect in many Diana teams, making it only recommended in scenarios where Diana is being used as more of a sub-DPS for another extra attack DPS.

C'mere、Milk & Pong! II: The card now discards up to 2 cards from hand and creates Heart Shakers for every card discarded + 1 via this card. This is a great option in many builds, provided they can activate the Resonance fully, as Heart Shakers are 2 hits each when discarded if all Resonances are used, which is more than any other Bullet type Diana can make. However, it can sometimes be a less reliable choice in scenarios where you do not do a lot of discards or are not using Pistol of Purification III, as it can be hard to activate all of the Resonance stacks she can make. Still, it is a great option purely for giving more discard ability even in teams that are not built around Heart Shaker DPS.

C'mere、Milk & Pong! III: The cost of the card changes to 0 and the effect becomes a transformation of all 0-cost [Exhaust] cards in hand into random Heart Bullets. While this can be quite strong with certain units who can make a lot of 0-cost [Exhaust] cards, like Tiphera, its randomness and the fact that the cards you’re converting are lost will generally be less consistent than alternative options for most content and is not a high recommendation to shoot towards unless you have a very specific combo in mind.

C'mere、Milk & Pong! IV: Now creates 1 of each Heart Bullet in hand. While this can be lower potential than alternative options, it has almost no drawback with it effectively just giving 2-3 Resonance, 1 Heart Shaker and 1 Heart Breaker. The lack of high requirements to play around makes this the go-to Epiphany for C’Mere for most decks, keeping the card in.

C'mere、Milk & Pong! V: Card is now a [Retain / Unique] that creates 1 Heart Shaker on every ‘[Retain]’ trigger and can convert all Heart Shakers in hand into Heart Breakers, if played manually. This is a solid card in prolonged fights, given you have the handspace for it, as it can effectively give a free Heart Shaker every turn with no downsides besides needing 2 hand space.

Neutral: Target Neutral Epiphany: Draw 1.
Draw 1 gives an efficiency similar to Divine's, enabling a much easier cycle and saving save data points for other areas of set-up like Neutral cards.

Divine: Which Divine Epiphany to go for will depend on what your team needs and which Epiphany you chose, but here are the main ones to look out for if you have spare Save Data: Draw 1, Cost-Reduction, 1 AP (C’Mere Milk & Pong! III).

Pistol of Purification I: Now gains 3 Resonance and activates Resonance 5 extra times if discarded (total of 6 Resonance activations). This is the go-to Epiphany as it not only gives Resonance but also activates 6 of them, making it great for both Resonance generation and activation.

Pistol of Purification II: Becomes a card that applies 1 Resonance for the next 5 [Haste] attack cards used. This is a great effect in scenarios where you are using a lot of [Haste] attack cards, which Diana’s own Heart Breaker builds often will. However, it lacks the Resonance consumption effect of other Epiphanies, making this variant primarily useful for decks with incredibly high discard amounts plus many [Haste] cards.

Pistol of Purification III: Simply activates Resonance 10 times on the target. Diana can potentially make close to 40 Resonance a turn in some super-optimized builds, which is an amount of discards that is not easily achievable; however, this card can lessen the amount of discards you need by 10, which makes it an amazing option in scenarios where you are generating a lot of Resonance (such as Heart Shaker builds).

Pistol of Purification IV: Changes to a card that scales its damage based on the number of [Bullet] cards discarded. While this can be weak in some sustained scenarios, it has an incredibly high cap in damage as there are ways to discard a great number of [Bullet] cards a turn via ego skills like Nia or Renoa’s, alongside additional card effects, making this a great option to consider for OTK content with Diana.

Pistol of Purification V: The card now does AOE damage and activates Resonance applied to all enemies 2 times. While this can be a nice AOE option for Diana, it can be awkward to use because Resonance is almost exclusively a single-target debuff, but this effect works best if you have applied it to many enemies; thus, it's an AOE option that lacks a way of applying the debuff in AOE for its best effect (besides Blooming Love II).

Neutral: Target Neutral Epiphany: Draw 1.
Draw 1 gives an efficiency similar to Divine's, enabling a much easier cycle and saving save data points for other areas of set-up like Neutral cards.

Divine: Which Divine Epiphany to go for will depend on what your team needs and which Epiphany you chose, but here are the main ones to look out for if you have spare Save Data: Vulnerable 2, Weakness Attack.

Blooming Love I: Draws 1 [Quietus] card, discards 1, and creates 2 random Heart Bullets IF the discard target was an ally combatant and not Diana herself. This is a great Epiphany if being used in a more supportive or sub-DPS role, such as when used alongside Renoa, as she will often discard other targets and not just herself in these situations.

Blooming Love II: Draws 2 [Quietus] cards, discards 2, and applies 1 Resonance to all enemies for the combined AP cost of the discard targets (max 6). This is the premier AOE option, when used alongside Pistol of Purification V, but it does have a lot of asterisks as it requires you to have high-cost cards to discard and multiple targets to get full value. Moreover, Diana is still not a highly recommended AOE unit even with these two Epiphanies together, as they lack synergy with most of the rest of her kit.

Blooming Love III: Discards up to 3 [Bullet] cards and draws a [Quietus] card for each discarded -1 (max 2, min 0). This effectively just increases the amount of potential discard and draw of the original card, but it can end up lowering in value if you lack specific [Bullet] targets or don’t have a specific build that wants to discard [Bullet] targets to begin with.

Blooming Love IV: Discards all [Bullet] cards from hand and does an extra attack for each discarded. This is a great option for additional damage, but it suffers from Diana already discarding a ton of [Bullet] cards herself, from her [Bullet] cards themselves, which can make it difficult to actually get full value out of. The go-to epiphany for damage.

Blooming Love V: Is now a [Unique] upgrade that draws 1 [Quietus] card a turn, automatically, if none are in hand. This is a comfort Epiphany as it will passively almost always get value when using Diana and has little to no downsides. In some scenarios, it might be preferred to use another Epiphany for the given situation, but it’s unlikely this Epiphany won’t at least be as good as well.

Neutral: Target Neutral Epiphany: N/A.
Blooming Love lacks Draw neutral access because of its innate draw and has extremely important epiphany options that might be avoided from taking a neutral instead.

Divine: Which Divine Epiphany to go for will depend on what your team needs and which Epiphany you chose, but here are the main ones to look out for if you have spare Save Data: Draw 1, Morale/Resolve (Blooming Love V).